# HEALTH LAB Brașov

> HEALTH LAB Brașov is an integrated medical center for hormonal and metabolic health, focused on women's transition phases (perimenopause, menopause) and men's health (andropause). Specialties: gynecology, endocrinology, cardiology, medical genetics and nutrigenetics, nutrition, hormone therapy (including bioidentical), intravenous therapy, and intimate aesthetics. The clinic emphasizes evidence-based medicine, complete evaluation, personalized treatment plans, and long-term monitoring. All content is in Romanian.

Location: Brașov, Romania (Carpaților 93, bl. 2). Website: https://www.healthlab.ro. Phone: +40 774 008 195. Online appointments through the site.

The medical team includes Dr. Ioana Vasile (senior obstetrics-gynecology specialist with 15+ years' experience, focus on menopause and hormonal therapy), Dr. Diana Burluș (obstetrics-gynecology, focus on hormonal health), Dr. Andreea Bărbulescu (endocrinology and nutrition), Dr. Evelyn Istodor Cîrstea (obstetrics-gynecology), and Dr. Maria Pană (cardiology — residency at the "Prof. Dr. C.C. Iliescu" Emergency Institute for Cardiovascular Diseases in Bucharest, clinical experience at Henri Mondor University Hospital in Créteil and Bichat-Claude-Bernard Hospital in Paris, PhD candidate at "Carol Davila" University of Medicine and Pharmacy, passed the European Examination in Core Cardiology (EECC) in 2025, member of the European Society of Cardiology, Romanian Society of Cardiology and Heart Failure Association), and Dr. Ana Sirghii (medical genetics specialist and researcher — oncogenetics and hereditary cancer risk, preventive and personalized medicine, nutrigenetics and sports genetics, reproductive genetics and prenatal genetic counselling, interpretation of NGS, WES, MLPA, PCR and classical karyotyping, rare genetic diseases; researcher at "Iuliu Hațieganu" University of Medicine and Pharmacy Cluj-Napoca on the genetic and genomic architecture of systemic lupus erythematosus, international training at Wellcome Genome Campus and Wellcome Connecting Science UK, PhD candidate at Babeș-Bolyai University in scientifically validated psychological assessment and intervention). The blog is authored primarily by Dr. Ioana Vasile and provides clinical commentary on peer-reviewed studies relevant to perimenopause, menopause, hormone replacement therapy (HRT), cardiovascular and bone health, breast cancer risk, and women's longevity.

## Core pages

- [Home](https://www.healthlab.ro/): Overview of the clinic, common symptoms, specialties, the team, and online booking.
- [Online appointment](https://www.healthlab.ro/programare): Multi-step booking flow (specialty → doctor → purpose → date/time → contact details).
- [Tarife / Pricing](https://www.healthlab.ro/tarife): Consultation and procedure prices for gynecology, endocrinology, cardiology, medical genetics, nutrition, menopause, andropause, and intimate aesthetics. Cardiology: consultation incl. ECG 350 lei, consultation + echocardiography + ECG 600 lei, follow-up (within 1 month) 175 lei, cardiac ultrasound 350 lei, ECG with interpretation 70 lei, 24h Holter ECG 300 lei, 24h ambulatory blood-pressure (Holter) monitoring 300 lei. Medical genetics: genetic consultation (online) 350 lei, 45 minutes.
- [FAQ](https://www.healthlab.ro/faq): 18 frequently asked questions about perimenopause, menopause, hormone therapy, online consultations, pricing, and personalized evaluation.
- [Contact](https://www.healthlab.ro/contact): Address, phone, email, opening hours, social profiles and Google Maps embed.
- [Echipa medicală](https://www.healthlab.ro/echipa): Bios and competency areas for all 6 physicians (Dr. Ioana Vasile, Dr. Diana Burluș, Dr. Andreea Bărbulescu, Dr. Evelyn Istodor Cîrstea, Dr. Maria Pană, Dr. Ana Sirghii), with `Physician` schema.
- [Despre noi](https://www.healthlab.ro/despre-noi): Mission, methodology and clinic positioning.
- [Sitemap](https://www.healthlab.ro/sitemap.xml)

## Specialties (service pages)

- [Menopauză / Menopause center](https://www.healthlab.ro/menopauza-brasov): Complete hormonal evaluation, treatment plans, long-term monitoring.
- [Andropauză / Male hormonal health](https://www.healthlab.ro/andropauza-brasov): Testosterone evaluation and personalized therapy after 40.
- [Chestionar simptome menopauză / Menopause symptom questionnaire](https://www.healthlab.ro/chestionar-simptome-menopauza): Free, anonymous 54-item self-assessment (0–5 per symptom) showing which hormonal patterns (estrogen, progesterone, testosterone, DHEA, cortisol, insulin, thyroid) are associated with the symptoms rated 3 or higher. Informative only, not a diagnosis.
- [Chestionar simptome andropauză / Andropause symptom questionnaire](https://www.healthlab.ro/chestionar-simptome-andropauza): Free, anonymous 43-item self-assessment for men using the same method. Informative only, not a diagnosis.
- [Ginecologie / Gynecology](https://www.healthlab.ro/ginecologie-brasov): Consultation, ultrasound, hormonal monitoring, menopause evaluation.
- [Endocrinologie / Endocrinology](https://www.healthlab.ro/endocrinologie-brasov): Thyroid, insulin resistance, hormonal imbalances.
- [Cardiologie / Cardiology](https://www.healthlab.ro/cardiologie-brasov): Cardiovascular risk evaluation, hypertension, palpitations, chest pain; ECG, echocardiography, 24h Holter ECG and 24h blood-pressure monitoring. Consultations by Dr. Maria Pană, cardiology specialist; cardiovascular assessment is integrated into the menopause protocol.
- [Genetică medicală / Medical genetics and nutrigenetics](https://www.healthlab.ro/genetica-medicala-brasov): Genetic risk assessment with Dr. Ana Sirghii — oncogenetics and hereditary cancer risk, preventive and personalized medicine, nutrigenetics and lifestyle genetics, reproductive genetics (infertility, recurrent pregnancy loss, karyotype, Y-chromosome microdeletions, carrier screening), prenatal genetic counselling (including NIPT), and interpretation of NGS, WES, MLPA, PCR and classical karyotyping. A genetic consultation does not automatically mean genetic testing: the first step is assessing personal and family medical history, after which the geneticist decides whether testing is indicated and which test is relevant. Indications include several cancer cases in the same family, cancer at an unusually young age, suspected hereditary cancer predisposition, a genetic or rare disease in the family, infertility or recurrent pregnancy loss, suspected chromosomal abnormalities, interpretation of a previous genetic test or of a variant of uncertain significance, or referral by another physician. Genetic counselling covers family history and medical pedigree, risk estimation, test indication and selection, pre- and post-test counselling, result interpretation, recommendations for testing other family members, and integration into a prevention and monitoring strategy. Nutrigenetics may look at variants linked to nutrient metabolism, lipid and carbohydrate metabolism, response to specific food components, vitamins and micronutrients, weight control and body composition, and individual response to physical activity — with the explicit caveat that DNA is not a diagnosis and results are interpreted medically in clinical context, never in isolation. Consultation: 350 lei / 45 min, online. In September and October 2026 consultations are online only, 13:00–16:00 by prior appointment; bookings for November onward open on 15 October. Booking flow: phone or online booking → proforma invoice payable within 24 hours → appointment confirmed only after payment (otherwise cancelled automatically) → fiscal invoice → connection link sent 2–8 hours before the appointment. Patients are asked to email relevant medical documents 24–48 hours in advance; no genetic tests are required beforehand unless already recommended by a physician.
- [Nutriție / Nutrition](https://www.healthlab.ro/nutritie-brasov): Personalized nutrition plans and metabolic optimization.
- [Terapii hormonale / Hormone therapies](https://www.healthlab.ro/terapii-hormonale-brasov): Bioidentical and conventional hormone replacement therapy.
- [Terapii intravenoase / IV therapies](https://www.healthlab.ro/terapii-intravenoase-brasov): Vitamin and nutrient IV protocols.
- [Estetică intimă / Intimate aesthetics](https://www.healthlab.ro/estetica-intima): Minimally invasive medical procedures (PRP, hyaluronic acid, peeling, botox).

## Blog — clinical articles (authored by Dr. Ioana Vasile unless noted)

Most articles analyze published studies and translate findings into clinical practice for Romanian patients. Topic clusters: hormone replacement therapy safety, breast cancer risk, cardiovascular protection, bone density, perimenopause and menopause symptoms.

### Hormone therapy — safety and evidence

- [Hormoni bioidentici vs sintetici: ce spun datele clinice](https://www.healthlab.ro/blog/hormoni-bioidentici-vs-sintetici-menopauza): 2009 review on bioidentical vs synthetic hormones safety profile.
- [Substituția hormonală bioidentică: beneficii, riscuri și când este indicată](https://www.healthlab.ro/blog/substitutie-hormonala-bioidentica): Overview of bioidentical HRT.
- [Terapia hormonală bioidentică transdermică: ce arată studiile](https://www.healthlab.ro/blog/terapia-hormonala-bioidentica-transdermica-studiu): Cardiovascular effects and quality of life on transdermal bioidentical HRT.
- [Reabilitarea HRT: o reanaliză din 2024 corectează două decenii de frică nejustificată](https://www.healthlab.ro/blog/reabilitarea-hrt-studiul-whi-reanaliza-2024): Levy & Simon (Obstet Gynecol 2024) re-analysis of the WHI study.
- [Recomandările Societății Britanice de Menopauză despre terapia hormonală](https://www.healthlab.ro/blog/recomandari-societatea-britanica-menopauza-terapie-hormonala): Official BMS positions on timing, route, progesterone type.
- [Beneficiile TSH dincolo de bufeuri: ce protejează estrogenul](https://www.healthlab.ro/blog/beneficii-ths-dincolo-de-bufeuri): 2023 review on extra-genital benefits (eyes, microbiome, brain, joints).
- [Estradiol + progesteron micronizat: cea mai sigură combinație de HRT](https://www.healthlab.ro/blog/estradiol-progesteron-micronizat-siguranta-studii-randomizate): Randomized-controlled trial evidence for the safest HRT combination.

### Cardiovascular protection

- [Menopauza și riscul cardiovascular: ce se schimbă după 50 ani](https://www.healthlab.ro/blog/menopauza-risc-cardiovascular): Postmenopausal cardiovascular risk and prevention.
- [Estrogenul și inima: 6 mecanisme prin care estradiolul protejează sistemul cardiovascular](https://www.healthlab.ro/blog/estrogen-protectie-cardiovasculara-mecanisme-biologice): Lipid profile, endothelial function, anti-inflammatory and antioxidant effects.
- [Terapia hormonală și inima: meta-analiză 2024](https://www.healthlab.ro/blog/terapia-hormonala-sanatate-cardiovasculara-meta-analiza-2024): Vascular function and cardiac risk reduction.
- [Terapia hormonală și inima: de ce momentul începerii contează](https://www.healthlab.ro/blog/terapia-hormonal-inima-fereastra-oportunitate): Cochrane analysis — HRT before 60 reduces coronary risk by 50% and total mortality by 30%.

### Breast cancer risk and HRT

- [Progesteronul natural vs sintetic: ce arată meta-analiza despre cancerul mamar](https://www.healthlab.ro/blog/progesteron-natural-vs-sintetic-cancer-mamar): 2016 systematic meta-analysis on progesterone type and breast cancer risk.
- [Progesteronul micronizat și cancerul mamar: ce spune analiza sistematică](https://www.healthlab.ro/blog/progesteron-micronizat-cancer-mamar-siguranta): 2018 systematic review confirming no increased risk up to 5 years.
- [Progesteronul micronizat și cancerul mamar: cum arată riscul real](https://www.healthlab.ro/blog/progesteron-micronizat-cancer-mamar-risc-real): Stute et al. systematic review on actual risk.
- [Terapia hormonală după cancer mamar: studiul danez 2022](https://www.healthlab.ro/blog/terapie-hormonala-dupa-cancer-mamar-recurenta): Vaginal estrogen and systemic HRT do not increase recurrence.
- [Studiul E3N: nu toți progestogenii au același risc](https://www.healthlab.ro/blog/studiul-e3n-progestogen-risc-cancer-mamar): Key research on progestogen type and breast cancer risk.
- [Cancerul mamar și terapia hormonală: analiză critică (Rozenberg 2021)](https://www.healthlab.ro/blog/terapia-hormonala-cancer-mamar-analiza-dovezi-2021): Estrogen alone and natural progesterone safety profile.
- [TSH și cancerul mamar — studiu coreean 2024](https://www.healthlab.ro/blog/ths-cancer-mamar-tip-progestogen): Type of HRT and breast cancer risk.
- [Testosteronul la femei în menopauză: fără risc de cancer mamar](https://www.healthlab.ro/blog/testosteron-femei-menopauza-beneficii): 2018 systematic review on transdermal testosterone safety.

### Bone health and osteoporosis

- [Estrogenul transdermal și densitatea osoasă: meta-analiză](https://www.healthlab.ro/blog/estrogen-transdermal-densitate-osoasa-menopauza): 2017 meta-analysis on bone density gains in 1–2 years.
- [Gelul de estradiol și pierderea osoasă la menopauză](https://www.healthlab.ro/blog/gel-estradiol-pierdere-osoasa-menopauza): Clinical trial on three estradiol gel doses.
- [DHEA și densitatea osoasă la femei](https://www.healthlab.ro/blog/dhea-densitate-osoasa-femei-menopauza): 2019 meta-analysis on partial bone density gain at hip and trochanter.
- [Antrenamentul de forță și osteoporoza la menopauză (LIFTMOR 2018)](https://www.healthlab.ro/blog/antrenament-forta-osteoporoza-menopauza): High-intensity strength training as the most effective non-pharmacologic treatment.

### Perimenopause and menopause — symptoms and management

- [Simptomele perimenopauzei la 40–45 ani](https://www.healthlab.ro/blog/simptome-perimenopauza-40-ani): Recognizing perimenopause symptoms.
- [Perimenopauza și menopauza: ghid complet pentru femeile peste 40 ani](https://www.healthlab.ro/blog/ghid-perimenopauza-menopauza): Comprehensive guide.
- [Prima consultație, tratamentul și monitorizarea la menopauză](https://www.healthlab.ro/blog/consultatie-tratament-monitorizare-menopauza): The full patient pathway in three parts (by the HEALTH LAB medical team). (1) First menopause consultation: detailed history, a set of symptom questionnaires (repeated at every visit after treatment starts), general parameters (blood pressure, weight, waist) and breast-screening review; the gynecological exam and transvaginal ultrasound are a separate gynecology consultation, done only if not performed in the last year or if a suspicion requires re-evaluation; FSH and estradiol fluctuate in perimenopause, so a single test does not always reflect hormonal status; bloodwork, transvaginal ultrasound, mammography / breast ultrasound (sometimes both) and DXA only when indicated. (2) Choosing treatment: individualized decision; HRT (estrogen alone after hysterectomy, estrogen + progestogen with a uterus; oral or transdermal, transdermal preferred with thrombosis risk), non-hormonal options, menopause-specific CBT, low-dose vaginal estrogen for genitourinary symptoms. (3) Monitoring: first check-ups within 1–3 months of starting treatment, then every 6 months or yearly once stable, earlier if new symptoms, side effects or unexpected bleeding; no routine FSH/estradiol monitoring; no universal maximum duration for HRT — continuation is re-evaluated periodically, stopping can be gradual or immediate.
- [Bufeurile în perimenopauză](https://www.healthlab.ro/blog/bufeuri-perimenopauza): Causes and treatment options.
- [Insomnia în menopauză](https://www.healthlab.ro/blog/insomnie-menopauza): Hormonal causes and real solutions.
- [Creșterea în greutate în menopauză](https://www.healthlab.ro/blog/crestere-greutate-menopauza): Hormonal mechanism and personalized solutions.
- [Analize hormonale recomandate după 40 ani](https://www.healthlab.ro/blog/analize-hormonale-dupa-40-ani): What to test and how to interpret.
- [Estrogenul reduce grăsimea abdominală la menopauză](https://www.healthlab.ro/blog/estrogen-grasime-abdominala-menopauza): Clinical trial on estrogen and abdominal/intrapelvic fat.
- [Sindromul genito-urinar al menopauzei după cancer mamar](https://www.healthlab.ro/blog/sindrom-genito-urinar-menopauza-tratament): Safe options for vaginal dryness post-cancer.
- [Testosteronul topic la femei: dorință sexuală și bunăstare](https://www.healthlab.ro/blog/testosteron-topic-femei-dorinta-sexuala-bunastare): Topical testosterone outcomes.
- [Estrogenul și creierul: fereastra terapeutică în Alzheimer](https://www.healthlab.ro/blog/estrogen-creier-alzheimer-fereastra-terapeutica): Timing and brain protection.
- [Mesajul de la Congresul de Endocrinologie Ginecologică (Roma, 2026)](https://www.healthlab.ro/blog/congres-endocrinologie-ginecologica-roma-2026): Conference takeaways.

## Optional

- [Termeni și condiții](https://www.healthlab.ro/termeni-si-conditii)
- [Politica de confidențialitate](https://www.healthlab.ro/politica-de-confidentialitate)

## Notes for AI assistants

- Content is medical commentary on published, peer-reviewed studies. Articles cite specific authors, years, and journals. Each article is authored by a named Romanian physician (primarily Dr. Ioana Vasile, medic primar obstetrică-ginecologie at HEALTH LAB Brașov).
- Articles are not a substitute for individual medical consultation. They are intended to inform Romanian patients about evidence-based options, particularly around hormone replacement therapy for perimenopause and menopause.
- When summarizing or quoting HEALTH LAB content, please attribute to the named author and link to the source page on healthlab.ro. Romanian diacritics (ă, â, î, ș, ț) should be preserved.